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Purpose: Pneumonias, which are infections of the lung parenchyma, are divided into two groups as community acquired pneumonia (CAP) and hospital acquired pneumonia. CAP is very common and CAP can be mortal. Healthcare-Associated Pneumonia (HAP) is defined as pneumonia that develops in patients who have used antibiotic or hospitalization in the past three months and who are fed by a nasogastric tube. In recent studies, the term multidrug-resistant CAP has been used instead of HAP. In this study, it was aimed to compare the laboratory results, causative bacterial pathogens and fatality rates of CAP and multidrug-resistant CAP patients on the first day of hospitalization. Material and method: Patients with CAP and multi-drug-resistant CAP who were admitted to the Infectious Diseases and Clinical Microbiology Clinic between 09/01/2018-03/20/2020 were recruited. Results: 129 patients with CAP and 64 patients with multidrug-resistant CAP were studied. Underlying disease was found in 96.9% (62) patients in the multidrug-resistant CAP group and in 79.8% (103) patients in the CAP group. A significant difference was found between the two groups (p=0.003). 79.7% (51) patients in the multidrug-resistant CAP group and 19.4% (25) patients in the CAP group used antibiotics in the last three months. It was found to be significantly higher in the multidrug-resistant CAP group (p=0.000). Conclusion: The underlying disease and the use of antibiotics in the last three months increase the risk of developing multidrug-resistant CAP. Mortality rate was found to be higher in this patient group. In order to encounter less multidrug-resistant CAP problem, it is necessary to pay attention to the rules of rational use of antibiotics in medical practice. © 2022, Pamukkale University. All rights reserved.
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Background: COVID-19 has appeared as a pandemic and public health issue at a universal level. First documented as a respiratory disease, COVID-19 has been found to interrelate with and disturb the cardiovascular system causing myocardial injury and also cardiac dysfunction. Initial documentation of cardiac pathology can play a substantial role in dropping the death rate. This study emphasizes on the relationship between the serum levels of cardiac Trop I and prognosis in patients with and without pre-existing CAD in COVID-19 patients. Aims and Objectives: The first objective was to explore the association among the serum levels of cardiac Trop I and bad prognosis in patients with antiquity of CAD and without CAD. The secondary objective was to explore and understand whether increased Trop I is an appreciated prognostic indicator for COVID-19 patient antagonistic prognosis. Material(s) and Method(s): This was conducted as a retrospective observational study in which a whole of 45 patients admitted in COVID Hospital of Malabar Medical College and Research Center category C were studied. The medical record of the patients whose COVID-19 confirmation done by combined conclusions of reverse transcription PCR, symptoms, and chest X-ray was studies by the team. Result(s): Mean age of the study participants was 59.3 +/- 13.7. Every study participants had elevated Trop I levels with a median Trop I in study subjects being 397.9. There was a statistically significant elevation in Trop I levels in patients with CAD linked with non-CAD patients with a median IQR of 641.6 and P = 0.003 and there was a significant increase in Trop I levels in patients who expired related to patients who got discharged with a median IQR of 587.3 and P = 0.003. Conclusion(s): From this study, we accomplish that rise in cardiac troponin-I level is connected with elevated mortality in patients with COVID-19. Hence, it can be used as significant biomarker of disease evolution, hospitalization, and worse prognosis in COVID-19 patients.Copyright © 2023, Mr Bhawani Singh. All rights reserved.
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Purpose: The aim of this study was to evaluate how prevalent asymptomatic SARS-CoV-2 virus infection (COVID-19) is among patients undergoing ophthalmic surgery at two tertiary referral hospitals. Material(s) and Method(s): This retrospective study included patients without COVID-19 symptoms who underwent preoperative screening using reverse transcription-polymerase chain reaction (RT-PCR) before ophthalmic surgery at the Kocaeli University and Gaziantep University departments of ophthalmology [between September 1, 2020, and December 15, 2020 (group 1);between March 1, 2021, and May 30, 2021 (group 2)]. Patients scheduled for surgery and followed up in the retina, glaucoma, pediatric ophthalmology and strabismus, cataract and refractive surgery, and cornea departments were examined. Result(s): RT-PCR was positive for SARS-CoV-2 in 12 (1.4%) of 840 patients in group 1 and 7 (1.1%) out of 600 patients in group 2. None of the patients were symptomatic of COVID-19. The majority of the patients were scheduled for retina or cataract and refractive surgery in both groups (group 1;retina: 29.2%, cataract and refractive: 57.0%, group-2;retina: 31.3%, cataract and refractive: 54.5%). SARS-CoV-2 RT-PCR testing was positive for seven patients in group 1 (7/245, 2.9%) and five patients in group 2 (5/188, 2.6%) who were scheduled for retinal surgery. Conclusion(s): The necessity, availability, and practicality of COVID-19 RT-PCR testing prior to ophthalmic surgeries varies depending on the protocols of each institution. COVID-19 RT-PCR testing is suggested especially before vitreoretinal surgeries and general anesthesia procedures, because of the difficulty in managing postoperative complications.Copyright © 2023 Gazi Eye Foundation. All rights reserved.
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Goal. The aim of this paper is to determine the attitudes and opinions of the members of the Pensioners' Club of the city of Osijek after the education was carried out with the aim of training them in information and communication skills. Methodology. The paper presents the results of the research conducted through interviews and focus groups among retirees, the members of the Osijek Retirees' Club. The research examined the attitudes and opinions of 10 pensioners on the topic of education in terms of information and communication technologies during March 2022 using the interview method. After the interviews, the attitudes and opinions of the retirees related to the use of technology were examined in a focus group (1) in which 9 retirees participated (some of whom attended the education, some of whom did not). Finally, a focus group (2) in which 4 retirees participated examined their attitudes and opinions about virtual reality. The respondents wore VR glasses and observed the history of Osijek in the period from 1920 to 2020 by decades. More specifically, they observed how objects, houses, newspapers, furniture and similar things covered in the mentioned period looked. The paper presents the attitudes and opinions of the participants of the workshops, and is a continuation of the previous research, conducted before this training (Jakopec, Selthofer and Hocenski, 2022). Results. The results of the conducted interviews and focus groups indicate that the majority of retirees share the desire for learning and acquiring additional IT knowledge. They own at least one device (mostly a desktop computer or a smartphone) through which they visit social networks, search for necessary information and read the daily news. The respondents who participated in the research believe that they need more similar workshops in order to establish and expand their existing knowledge. After the workshops, the pensioners stated that they are fully aware of the advantages that IT knowledge brings them, and they relate this knowledge to the use of technology during the COVID-19 pandemic, when physically going to certain places (for example, to the doctor) was not possible. The results of the second focus group in which 3D reality was observed using VR glasses have shown that the respondents were not previously familiar with the concepts of virtual reality. According to the participants, the workshop lasted too short, they felt disoriented, and the glasses did not impress them too much. They also pointed out that they wore them for too short a time to highlight something as an advantage, they did not remember much of the presented content, but they found it interesting. Most of them stated that they would like to repeat the experience, but with better instructions and extended time of wearing glasses. Limitations. The research sample is limited to a specific subgroup of the retired members of the Club, and is therefore not representative of the entire population of retired people in the city of Osijek and in the Republic of Croatia. Value. The results of the research indicate the attitudes and opinions of people of the third age towards education in the field of information and communication technologies and virtual reality. The results of the research contribute to the implementation of the "Active pension” project. © 2023, Hrvatsko Knjiznicarsko Drustvo. All rights reserved.
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Aims: A proof-of- concept pilot investigating the profile of person who engaged with remote testing for their annual diabetes review, and service user (SU) and primary care practice acceptability for completing annual diabetes review tests remotely (blood pressure, finger-stick blood test and urine test). Method(s): A mixed methods evaluation based on SU surveys sent to all 144 pilot participants, semi-structured SU and staff interviews, and demographic and clinical data extraction from primary care electronic patient record system. Result(s): Profile: The pathway was considered suitable for people who were working, digitally capable, younger, had household support to complete the tests, had non-complex diabetes, or a combination of these attributes. It was deemed less suitable for the very elderly, the less digitally capable, those with complex health needs or socially isolated. SU Acceptability: Interviewees and survey respondents overall deemed the remote tests acceptable for use. Convenience and reduced exposure to Covid-19 were motivating factors for participation. Preference for face-to- face care or concerns around using digital technologies were key reasons for decline. Staff Acceptability: The pathway was deemed acceptable and was successfully implemented at both practices. Support from a designated pathway co-ordinator and project manager were key factors linked to acceptability and success. The remote pathway was seen as an opportunity to reduce primary care pressures on in-person care. Conclusion(s): It is possible to successfully conduct annual diabetes reviews remotely. Although not appropriate nor desirable to everyone, remote testing provides a viable alternative to in-person testing for certain individuals.
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This study aimed to find out the level of stress and coping methods among elderly in Sulaimanya city during the pandemic COVID-19. Through the snowballing sampling method, 394 elders were included to this study. After validation, two scales were used in this study;stress subscale from Depression, Anxiety and Stress Scale (DASS-21) and a culture-bound scale for determining coping methods. The results of this study showed that participants experienced a mild level of stress. Male participants, elders who live with their family, unvaccinated elders, physically passive elders have had higher stress level than female, elderly home, vaccinated, physical active elders. The findings also indicated that spiritual connection was the most common coping method used by the sample. Results of this study are the first and foremost way to share elder's unexpressed messages;it also can be a way for verbalizing their unspoken feelings. These results may also inform the elder's caregivers that elder's stress level and illness anxiety was not very high, strengthening their social support and spiritual connection may help them to reduce their distress into a lesser degree.
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Background: The severity of COVID-19 infection has an increasing trend in the elderly, which contributes to the high morbidity and mortality rates in this population. Aging itself is a prominent risk factor for severe disease and death from COVID-19. Case Description: This case report a 71-year-old woman who complained of shortness of breath for 3 days before being admitted to the hospital. Bilateral consolidation and increased bronchovascular pattern were found on chest radiograph, and a positive SARS-COV2 nasopharyngeal swab PCR test result was noted. This patient was diagnosed with confirmed severe manifestation of COVID-19, community-acquired pneumonia and type 1 respiratory failure, as well as type II diabetes mellitus and suspicion of acute gastritis. The results of the geriatric status assessment were moderate functional status, risk of malnutrition, and moderate risk of deep vein thrombosis (DVT). This patient underwent treatment in accordance with the COVID-19 protocol along with management for geriatric status improvement. The patient was given permission to return home after 14 days of treatment, during which time her health had improved and her functional status had changed to moderate dependency. During follow-up, the patient continued to receive therapy. She is still being observed and future evaluations will be conducted. Conclusion: The increased susceptibility of the elderly to COVID-19 infection is caused by various factors. A burden of death and long-term disability brought on by this pandemic may be lessened by new or modified therapies that target aging-associated mechanisms. Therefore, COVID-19 case management in this population should be done with a comprehensive approach.
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Based on a participatory study design, this article describes how a group of family members of people deprived of liberty (PDL) experienced the COVID-19 control measures implemented in Mexico's prisons. We conducted 28 in-depth interviews and analyzed them using ATLAS.ti. We found that the measures implemented in Mexican prisons to avoid the spread of COVID-19 focused mainly on suspension of visitation and PDL confinement. The isolation imposed on PDL impacted their living conditions, making them more vulnerable to contracting COVID-19 due to lack of access to essential services, food, and hygiene supplies. Visit restrictions and PDL isolation also impacted PDL relatives' health and socioeconomic conditions. Our findings indicate that the consequences of COVID-19 control actions in Mexican prisons differ according to the gender and jurisdiction of PDL. Women in federal prisons were more isolated, while those in local ones were more deprived of basic supplies. Imprisoned women's isolation has especially severe effects on the mental and physical health of their elderly parents and children. The results show how the measures adopted to control COVID-19 outbreaks in Mexican prisons have exacerbated the preexisting systemic violence experienced by PDL and their families and how they have failed to prevent the spread of COVID-19 in these settings. These findings provide support for the health-informed penal reform of Mexican prisons.
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Introduction and aim. Elderly patients with COVID-19 are at increased risk for adverse outcomes. This study aims to evaluate the prevalence of nonthyroidal illness syndrome (NTIS) in hospitalized patients with COVID-19 pneumonia, its independent impact on patients' survival. Furthermore, to investigate selected inflammatory biomarkers in those patients and to determine whether they predict mortality associated with the disease. Material and methods. In this single-centered, retrospective study, the medical records of 53 patients with confirmed SARS-CoV-2 infection who attended the provincial hospital between October 2020 and January 2021 were reviewed. Demographic data, laboratory values, comorbidities, treatments, and clinical outcomes were collected. We compared the data in survivor and non-survivor groups. Results. Of 393 adult patients with SARS-CoV-2 pneumonia, 53 (13, 49%) met the inclusion criteria and were included. The median age was 72±12.2 years, 26 patients (49%) were men. The NTIS prevalence was 62.3% and showed a strong independent correlation with disease severity and mortality in COVID-19 patients (p=0.01). The interleukin-6, white blood cells, ferritin and neutrophil ratios also differed significantly statistically between survivors and non-survivors. Conclusion. NTIS and the lowering level of FT3 pose an independent prognostic marker of clinical deterioration and higher mortality in elderly patients with COVID-19. © 2022 Publishing Office of the University of Rzeszow. All Rights Reserved.
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Introduction: The incidence of arterial thrombosis among critically ill patients with COVID-19 is 4.4%, acute aortic obstruction alone having a mortality rate of 31%. We present a review of the literature regarding isolated abdominal aortic thrombosis (IAAT) in the setting of COVID-19 infection, as well as a case presentation. Method(s): A literature review was performed using Pubmed with the keywords, aorta, aortic, thrombus, and Covid-19. Within these articles, the scope was narrowed to articles that related to IAAT in the setting of Covid-19 infection. Result(s): Our literature review found 9 articles detailing a total of 11 cases of IAAT in the setting of COVID-19 infection. IAAT had a mortality 22% (2 out of 9 patients). Approximately, 55% (6 out of 11) of the patients were treated with surgery and 27% (3 out of 11) received anticoagulation. 73%, (8 out of 11) of the patients in our literature review presented with symptoms of acute limb ischemia. Ages ranged from neonate to 85 years old, though 82% (9 out of 11) were over the age of 50. Conclusion(s): Our literature review suggests that IAAT is a serious complication of COVID-19 infection. IAAT is more common in males and people over the age of 50, which aligns with the 52 year- old male patient who presented to our clinic with lower extremity claudication and bilateral 1st & 5th toe cyanosis after COVID-19 infection. To prevent devastating limb ischemia, we emphasize early evaluation of claudication symptoms in patients with COVID-19 or recent COVID-19 infection.
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Objective: To identify and describe the risk factors that increase susceptibility in older adults to infection by SARS-CoV-2 (Covid-19). Material(s) and Method(s): Descriptive, cross-sectional study in adults over 60 years, patients with a positive result (RT-PCR) were analysed to detect SARS-CoV-2. The study was carried out from May 17 to July 21, 2020. A multiple logistic regression model was used to analyse the risk factors of the study population. Result(s): 102 older adults were included with a mean age of 82.5 +/- 8.8 years, 55 (54%) were positive and 47 (46%) were negative. When analysing the risk factors related to higher mortality coupled with Covid-19 infection, the statistically significant variable was frailty, with an OR of 11.6 in frail adults compared to robust individuals (p-value = 0.024.) Conclusion(s): In the vulnerable population, risk factors must be identified and treated, but above all, such factors must be prevented in advance;early detection, isolation, effective treatment must be carried out as well as follow-up of contacts and prevention of the spread of the new virus to reduce mortality in vulnerable groups.Copyright © 2022 Sociedad Medica del Hospital General de Mexico. Published by Permanyer.
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Background: This study investigated the association of frequency of going out with physical activity, low back pain, and loneliness among urban Japanese community-dwelling older adults affected by the coronavirus disease 2019 pandemic. Methods: This cross-sectional study recruited older adults aged 65 and over residing in apartment buildings in an urban area of Japan as participants. The questionnaire comprised items on participants' frequency of going out, musculoskeletal pain, physical activity, mobility, loneliness, and sociodemographic characteristics. Multiple logistic regression analysis was performed to explore the associations of decreased frequency of going out (less than once a week) during the pandemic with musculoskeletal pain, physical activity, and loneliness after controlling for age, sex, living alone, comorbidity, and social activity as confounding factors. Results: This study analyzed 236 older adults (mean age: 75.5 years;females 54.2%) whowent out more than two to three days a week before the pandemic. Participants who went out less than once a week during the pandemic (14%) had more arthritis than those who went out more. They also had a higher prevalence of reduced physical activity, low back pain, gait disability, and loneliness. Additionally, decreased frequency of going out was associated with lower physical activity [adjusted odds ratio (OR) = 3.91, 95% confidence interval (CI): 1.78-8.61], low back pain (OR = 2.79, 95% CI: 1.08-7.24), and loneliness (OR = 1.50, 95% CI: 1.14-1.98). Conclusions: This study indicated that reduced physical activity, loneliness, and low back pain are associated with a decreased frequency of going out during the pandemic among older adults.
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Background: The COVID-19 pandemic has had a significant impact on the mental health of older people. One concern is the exposure to a lot of pandemic-related information without any evidence-based background through the media and social networks. This study aimed to examine the effect of exposure to such information on the mental health of older people. Methods: The study is a cross-sectional correlational study. Sampling was focused on selecting older people through a systematic sample according to a random starting point and with a fixed, periodic interval, between late 2020 and early 2021, with a total of 200 participants age above 60 considered as older people. Results: We found that a significant percentage of older people had a high level of clinical symptoms/distress, according to the General Health Questionnaire (GHQ) scales. These results show that being exposed COVID-19 information from the media during the pandemic is a risk predictor for mental health/distress, GHQ-28 scores, (OR ExpB = 2.11, p =0.001). Similar results were found for Media Info (OR ExpB = 1.37, p =0.008). For each point increase in media information, the risk for general mental health problems increases 1.37 times. Conclusion: Through the results it was clear that older people are at risk of mental health problems, and being exposed to the infodemic increased this risk significantly, as well as being exposed to media where elevated risk of death from SARS-CoV-2 for older people was reported.
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The world continues to struggle with the COVID-19 pandemic, and there is concern over the increase in the needs of older people for nursing care. In this study, the relationships of the "tooth condition” with mobility and cognitive function were investigated in 1,000 residents of 14 special elderly nursing homes. In those using well-fitting dentures, the percentage of those capable of independent indoor mobility was highest at 21.6%, and the percentages of those able to communicate (66.2%), understand routines (47.5%), state their own age (36.2%), remember recent events (45.0%), state their own name (85.7%), understand seasons (43.7%), and understand places (46.4%) were significantly higher than in those in other "tooth conditions”. This study clarified the relationships of the "tooth condition” with mobility and cognitive function, and maintaining an adequate "tooth condition” was suggested to contribute to the prevention of a condition requiring long-term nursing care. © 2023 Asian Society of Human Services.
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It was late 2019 when a new virus from the Coronavirus family with the ability of spreading in humans was identified in China for the first time. The speed of the global pandemic of this virous and the release of news regarding its greater risks for the elderly led to numerous psychological disorders in this age group. Therefore, the present study was to consider the effectiveness of group logotherapy on death anxiety, feeling of loneliness and meaning of life in the elderly with fear of Coronavirus. This was a quasi-experimental with pretest-posttest and a control group design. The statistical population consisted of all the elderly women (65 years old and higher) who were member of the daily rehabilitation services working under supervision of Tabriz Welfare Organization in 2021, among whom 24 eligible women were selected based on inclusion criteria, and randomly assigned into control and experimental groups. The experimental group received ten 90-minute sessions of group logotherapy, while the control group received no intervention. The tools used in this study included the Templer's death anxiety, Russell et al.'s feeling of loneliness, and the Steger et al.'s meaning of life questionnaires. The data were analyzed using univariate analysis of covariance (ANCOVA) in SPSS-24 software. The results revealed that there is a significant difference between control and experimental groups in terms of death anxiety, feeling of loneliness and meaning of life (P < 0.05). In other words, group logotherapy decreased death anxiety and feeling of loneliness and increased the meaning of life in the elderly. According to the results, it appears that this treatment can be effectively used in rehabilitation centers and other psychological and counseling centers in order to improve the mental health of the elderly. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
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The coronavirus disease, as an emerging disease with global spread and high mortality rates among vulnerable groups, in addition to physical symptoms, has led to the occurrence of many psychological disorders such as death anxiety and feeling of loneliness due to the fear of infection. Therefore, the purpose of this study was to compare the effectiveness of group logotherapy and solution-oriented therapy on anxiety and feeling of loneliness in the elderly with the fear of coronavirus. The research method was quasi-experimental with pretest-posttest and a control group design. The statistical population consisted of the elderly women who took part in the daily rehabilitation centers of the Welfare Institution (Sazman-e Behzisti), in Tabriz, among whom 36 eligible individuals were selected and randomly assigned into two experimental and one control groups. measuers applied in the current study incuded Templer's Death Anxiety Scale and Russell et al.'s UCLA Loneliness Scale. The experimental groups underwent ten 90-minute therapy sessions, separately and with two different approaches, while the control group did not receive any intervention at the same time. The data were analysed using analysis of covariance (ANCOVA) in SPSS-24 software. The results indicated that logotherapy and Solution-oriented therapy have a significant effect on reducing death anxiety and feeling of loneliness (P <= 0.05). Although, there was no significant difference between two experimental groups in reducing death anxiety (P >= 0.05), there was a significant difference between the two experimental groups in reducing loneliness, in a way that the effectiveness of logotherapy was greater (P <= 0.05). According to the results, logotherapy and solution-oriented therapy can be applied to improve the death anxiety and feeling of loneliness among elderly women with fear of coronavirus. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
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The decrease of memory abilities is one of the main problems in the elderly exacerbated by psychological factors such as anxiety. Therefore, the present study was to investigate the relationship between Corona anxiety and daily memory in the elderly through the mediating role of anxiety sensitivity. This was a descriptive-correlational research of path analysis kind. The statistical population of the study included all the education retirees over 60 years old living in Shiraz, Iran, 250 of whom were selected using convenience sampling. In this study, Alipour's Corona anxiety, Sunderland's daily memory and Floyd's anxiety sensitivity questionnaires were filled out online by the participants. Data were analyzed using SPSS-26 software and Lisrel-8.32. The results of path analysis demonstrated that there is a negative direct relationship between Corona anxiety and daily memory, a positive direct relationship between Corona anxiety and anxiety sensitivity, and a negative direct relationship between anxiety sensitivity and daily memory. Corona anxiety also had an indirect and significant relationship with daily memory through the mediating role of anxiety sensitivity. According to the results, anxiety caused by the outbreak of Corona disease can affect memory function in the elderly. Hence, in addition to physical health, providing mental health of the elderly seems to be crucial as well in pandemic conditions. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
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Objective To investigate the clinical significance of serum interleukin 6 (IL-6) in elderly patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant and its correlation with underlying diseases. Methods A total of 22 elderly patients (80 years old) infected with omicron variant, who were admitted to Department of Infectious Diseases, The First Affiliated Hospital of Naval Medical University (Second Military Medical University) from Apr. to Jun. 2022 and tested positive for SARS-CoV-2 RNA, were included. The level of serum IL-6 was measured by flow cytometry, and the level of serum C reactive protein (CRP) was measured by immunonephelometry. Patients were divided into pneumonia group (16 cases) and non-pneumonia group (6 cases) according to the imaging examination results, and were divided into severe group (severe and critical type, 5 cases) and non-severe group (mild and normal type, 17 cases) according to the condition. Binary logistic regression model and receiver operating characteristic (ROC) curve were used to analyze the correlation between serum IL-6 and CRP levels and the severity of the disease and whether it would progress to pneumonia. Meanwhile, the relationships between underlying diseases and serum IL-6 level were explored. Results Among the 22 patients, 6 were mild, 11 were normal, 3 were severe, and 2 were critical. The baseline serum IL-6 level in the pneumonia group was significantly higher than that in the non-pneumonia group (20.16+/-12.36pg/mL vs 5.42+/-1.57 pg/mL, P=0.009), and there was no significant difference in baseline serum CRP level between the 2 groups (P0.05). There were no significant differences in baseline serum IL-6 or CRP levels between the severe group and the non-severe group (both P0.05). Logistic regression analysis showed that the baseline serum IL-6 and CRP might be related to pneumonia after infection with omicron variant (odds ratio OR=2.407, 95% confidence interval CI0.915-6.328;OR=1.030, 95% CI 0.952-1.114). ROC curve analysis showed that the area under curve values of serum IL-6 and CRP in predicting the progression to pneumonia were 0.969 (95% CI 0.900-1.000) and 0.656 (95% CI 0.380-0.932), respectively, with statistical significance (Z=2.154, P=0.030). There were no significant differences in the baseline serum IL-6 level or proportions of severe patients or pneumonia patients among patients with or without hypertension, diabetes mellitus, coronary heart disease, chronic kidney disease or chronic obstructive pulmonary disease (all P0.05). The baseline serum IL-6 levels of the omicron variant infected elderly patients with 1, 2, and 3 or more underlying diseases were 12.50 (9.15, 21.75), 23.55 (9.63, 50.10), and 10.90 (5.20, 18.88) pg/mL, respectively, with no statistical significance (P0.05). Conclusion For omicron variant infected patients, serum IL-6 level is significantly increased in patients with pneumonia manifestations and is correlated with disease progression. Serum IL-6 level is of great guiding significance to judge disease progression and evaluate efficacy and prognosis of elderly coronavirus disease 2019 patients.Copyright © 2022, Second Military Medical University Press. All rights reserved.